Analysis of CXCL12 3'UTR G>A polymorphism in colorectal cancer
نویسندگان
چکیده
منابع مشابه
CXCL12-G801A polymorphism modulates risk of colorectal cancer in Taiwan
INTRODUCTION The chemokine CXCL12, designated stromal cell-derived factor-1 (SDF-1), plays a significant role in many cancer metastases. Previous studies have shown that CXCL12-G801A, a single nucleotide polymorphism (SNP) in the 3' untranslated region, correlates with breast and lung cancer in Iran. The aim of this study was to evaluate the association of the gene variant CXCL12-G801A with col...
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15 صفحه اولPolymorphism and circulating levels of the chemokine CXCL12 in colorectal cancer patients.
The chemokine CXCL12, also known as stromal cell-derived factor-1 (SDF-1), is a small protein that regulates leukocyte trafficking and is variably expressed in a number of normal and cancer tissues. CXCL12 as ligand and its receptor CXCR4 have been implicated in colorectal cancer (CRC) progression including angiogenesis and metastasis. A CXCL12 gene variant CXCL12-A (CXCL12-G801A, a single nucl...
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ژورنال
عنوان ژورنال: Oncology Reports
سال: 2007
ISSN: 1021-335X,1791-2431
DOI: 10.3892/or.18.6.1583